Study uncovers why COVID-19 is more deadly for some people with diabetes than others

Type 1 diabetes and heart attack

Tartalom

    DOI: Euglycemic diabetic ketoacidosis eu-DKA is a rare life-threatening complication associated with the use of SGLT2 inhibitor that may be unnoticed, particularly in a pandemic setting, due to the absence of significant hyperglycemia, delaying its treatment.

    type 1 diabetes and heart attack

    In this report, we describe a case of a year-old patient who presented an elevated anion gap metabolic acidosis during a SARS-CoV-2 infection and was diagnosed with SGLT2-associated euglycemic diabetic ketoacidosis. COVID may increase patients' insulin demand, present gastrointestinal symptoms, and increase the production of ketone bodies.

    type 1 diabetes and heart attack

    This situation can be worsened in susceptible diabetic patients on SLGT2 inhibitors, due to the persistent glycosuria, which can cause volume depletion.

    Recently some authors recommended that insulin-deficient patients or those type 1 diabetes and heart attack SGLT2 inhibitors should monitor for ketosis using available home testing kits in case of infections and should discontinue the medication in case of COVID Given the increased use of this drug class in the management of type 2 DM patients due to its reduction of cardiovascular risk, we set out to emphasize the importance for the medical community to consider the possibility of eu-DKA on SARS-CoVinfected patients using SLGT2 inhibitors, so physicians can provide these patients with appropriate therapy promptly.

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    type 1 diabetes and heart attack